Investigation into the temporal stability of aqueous standard solutions of psilocin and psilocybin using high performance liquid chromatography
N Anastos, NW Barnett, FM Pfeffer
School of Biological and Chemical Sciences, Deakin University, Geelong, VIC 3217, Australia
SW Lewis*
Department of Applied Chemistry, Curtin University of Technology, GPO Box U1987 Perth, Western Australia 6845 E-mail: S.Lewis@curtin.edu.au
Science & Justice 2006 46 91 - 96 Received 19 July 2005 accepted 06 October 2005
This paper reports an investigation into the temporal stability of aqueous solutions of psilocin and psilocybin reference drug standards over a period of fourteen days. This study was performed using high performance liquid chromatography utilising a (955% vlv) methanol: 10 mM ammonium formate, pH 3.5 mobile phase and absorption detection at 269 nm. It was found that the exclusion of light significantly prolonged the useful life of standards, with aqueous solutions of both psilocin and psilocybin being stable over a period of seven days.
N Anastos, NW Barnett, FM Pfeffer
School of Biological and Chemical Sciences, Deakin University, Geelong, VIC 3217, Australia
SW Lewis*
Department of Applied Chemistry, Curtin University of Technology, GPO Box U1987 Perth, Western Australia 6845 E-mail: S.Lewis@curtin.edu.au
Science & Justice 2006 46 91 - 96 Received 19 July 2005 accepted 06 October 2005
This paper reports an investigation into the temporal stability of aqueous solutions of psilocin and psilocybin reference drug standards over a period of fourteen days. This study was performed using high performance liquid chromatography utilising a (955% vlv) methanol: 10 mM ammonium formate, pH 3.5 mobile phase and absorption detection at 269 nm. It was found that the exclusion of light significantly prolonged the useful life of standards, with aqueous solutions of both psilocin and psilocybin being stable over a period of seven days.
